Author's response to reviews Title: Nuclear expression of Rac1 in cervical premalignant lesions and cervical cancer cells Authors:
نویسندگان
چکیده
Miguel A Mendoza-Catalan ([email protected]) Gema R Cristobal-Mondragon ([email protected]) Jesus Adame-Gomez ([email protected]) Heidi N del Valle-Flores ([email protected]) Jose F Coppe ([email protected]) Laura Sierra-Lopez ([email protected]) Mirna A Romero-Hernandez ([email protected]) Luz del Carmen Alarcon-Romero ([email protected]) Berenice Illades-Aguiar ([email protected]) Eduardo Castañeda-Saucedo ([email protected])
منابع مشابه
Correlation of P16 (Ink4a) and CK17 to HPV (16E6+18E6) in Premalignant and Malignant Lesions of Uterine Cervix: A Clinicopathologic Study
Background: This research was accomplished to evaluate the IHC expression of p16 (ink4a) and CK17 in low grade cervical intraepithelial lesions (LSIL), high grade cervical intraepithelial lesions (HSIL) and invasive cervical carcinomas and to assess their correlation to HPV (16E6+18E6). Methods: The study...
متن کاملDetention of HPV L1 Capsid Protein and hTERC Gene in Screening of Cervical Cancer
Objective(s): To investigate the expression of human papilloma virus (HPV) L1 capsid protein, and human telomerase RNA component (hTERC) in cervical cancer and the role of detection of both genes in screening of cervical cancer. Materials and Methods: A total of 309 patients were recruited and cervical exfoliated cells were collected. Immunocytochemistry was employed to detect HPV L1 capsid...
متن کاملAssociation of E6 gene expression of high risk human papillomaviruse HPV 18 in patients with Cervical squamous cell dysplasia and Cancerous Lesions
Abstract Background and Aims: Cervical cancer is among leading causes of cancer related death in women and human papilloma virus (HPV) is one of the important risk factor of this cancer. The aim of the present study was to develop a PCR method for identification of a high carcinogenic type of HPV, HPV 18 using E6 gene as a marker in patients with cervical cancer Materials and Methods: 9...
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EVALUATION OF THE EFFECTS OF IBUPROFEN CYTOTOXIC DOSE ON EXPRESSION LEVEL OF EXTRACELLULAR MATRIX DEGRADING MMP-9 AND ANTI-METASTASIS NM23 GENES IN CERVICAL CANCER CELLS
Background & Aim: Although studies have shown that ibuprofen has anticancer effects on many cancer cells, the mechanism of the ibuprofen anticancer effect in cancer cells is not still well understood. The aim of this study was to investigate the effect of cytotoxic concentration of ibuprofen on the expression level of MMP-9 and NM23 genes in cervical cancer cells. Materials & Methods: During t...
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